Time-dependent progression of neurogenic lower urinary tract dysfunction after spinal cord injury in the mouse model
نویسندگان
چکیده
This is the first paper to evaluate time-course changes of bladder dysfunction associated with mechanosensitive channels in a mouse model.
منابع مشابه
Post-trauma Bladder Management Strategy Influences Lower Urinary Tract Dysfunction after Spinal Cord Injury in the Mouse Model
Hypothesis / aims of study Spinal cord injury (SCI) rostral to the lumbosacral level eliminates voluntary and supraspinal control of voiding, leading initially to areflexic bladder and urinary retention, and then to a development of neurogenic lower urinary tract dysfunction (LUTD) such as detrusor overactivity (DO) and inefficient voiding due to detrusor sphincter dyssynergia (DSD). Although m...
متن کاملGuidelines on neurogenic lower urinary tract dysfunction.
itool=iconabstr 8. Chen PH, Hsueh HF, Hong CZ. Herpes zoster-associated voiding dysfunction: a retrospective study and literature review. Arch Phys Med Rehabil 2002;83:1624-1628. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12422336&dopt =Abstract&itool=iconabstr 9. Greenstein A, Matzkin H, Kaver I, Braf Z. Acute urinary retention in herpes genitalis infection....
متن کاملPathophysiology, Clinical Importance, and Management of Neurogenic Lower Urinary Tract Dysfunction Caused by Suprasacral Spinal Cord Injury
Management of persistent lower urinary tract dysfunction resulting from severe thoracolumbar spinal cord injury can be challenging. Severe suprasacral spinal cord injury releases the spinal cord segmental micturition reflex from supraspinal modulation and increases nerve growth factor concentration in the bladder wall, lumbosacral spinal cord, and dorsal root ganglion, which subsequently activa...
متن کامل[Urinary tract dysfunction in spinal cord injury patients].
Spinal cord injury (SCI) results with paralysis but also with micturition dysfunction; therefore rehabilitation management and long-term follow-up include lower urinary tract care in order to prevent upper urinary tract pathology and complications. That comprises timely and standardized neurological and urological diagnostics and eliminatory techniques with intermittent catheterisation in major...
متن کاملDysfunction of lower urinary tract in patients with spinal cord injury.
Over the past 50 years, the mortality for urorenal cause in patients with spinal cord injuries (SCI) has decreased from over 75% to 2.3%, as a result of dramatic improvements in the diagnosis and management of lower urinary tract dysfunction (LUTD). The aims of this chapter are to assess the physiopathology of upper and lower motor neuron lesion on bladder and sphincter function after SCI, to g...
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ژورنال
عنوان ژورنال: American Journal of Physiology-renal Physiology
سال: 2021
ISSN: ['1522-1466', '1931-857X']
DOI: https://doi.org/10.1152/ajprenal.00622.2020